Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.2
USERS' SCORE
Good
Based on 13 Reviews
8.2
Supplement Facts
Serving Size:   1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%

Top Medical Research Studies

We explored the relationship between vitamin D (VD) supplementation and the risk of ear infections, specifically in children who frequently suffer from acute otitis media (AOM). The study involved 116 children with a history of recurrent ear infections, who were randomly assigned to receive either a daily dose of 1000 IU of vitamin D or a placebo for four months. Their number of AOM episodes was monitored for six months after the treatment period.

Our findings were quite revealing: the children who received vitamin D supplements had a significantly lower incidence of AOM compared to those who were given the placebo. Specifically, only 26 children in the vitamin D group experienced at least one episode of AOM, versus 38 in the placebo group—a notable difference that became even more pronounced when looking specifically at uncomplicated AOM cases.

We concluded that vitamin D deficiency is common among children who frequently experience ear infections. By restoring serum vitamin D levels to above 30 ng/mL through supplementation, we observed a significant reduction in the risk of uncomplicated AOM. This suggests that vitamin D could play a beneficial role in managing ear infections in children prone to these issues.
Read More
9
Vitamin D's role in ear infections
We investigated how vitamin D levels affect the occurrence of ear infections, specifically in children aged 2 to 7. By looking at data from a pediatric clinic in northwest Romania, we enrolled 118 children—87 with recent ear infections and 31 who hadn't experienced any episodes. This allowed us to compare vitamin D levels across different types of ear infections, like Acute Suppurative Otitis Media and Serous Otitis Media.

Our findings revealed that children suffering from these infections had notably lower vitamin D levels compared to the control group. The children with Acute Suppurative Otitis Media showed the most significant deficiencies. We found a clear link: as vitamin D levels decreased, the frequency of ear infections increased. Logistic regression pointed out that vitamin D insufficiency boosted the odds of ear infections significantly, while Poisson regression established a strong correlation between low vitamin D status and the incidence of these infections.

Overall, these results indicate that low serum vitamin D may play a critical role in the risk of developing ear infections in young children. This suggests that screening and potentially supplementing vitamin D could be valuable strategies for reducing the frequency of ear infections and their associated complications. By addressing this modifiable risk factor, we can help improve the health and quality of life for many children.
Read More
9
Vitamin D enhances tympanoplasty outcomes
We explored how vitamin D (VD) levels influence the outcomes for patients undergoing Type 1 tympanoplasty (T1T), which is a common surgery for chronic ear infections. In our study, we divided 101 patients into four groups based on their VD levels, ranging from severe insufficiency to optimal levels.

Over a 12-month follow-up, we observed that patients with optimal VD levels had significantly higher graft success rates and greater improvements in hearing. Additionally, these patients experienced fewer postoperative infections.

Our findings highlight the importance of monitoring vitamin D levels in patients with chronic ear issues. We believe that addressing VD deficiency could enhance the success of tympanoplasty, suggesting that vitamin D replacement therapy might be beneficial for those with low preoperative levels.
Read More

Most Useful Reviews

9
Effective hay fever treatment
2 people found this helpful
As someone who suffers from hay fever, I found that taking vitamin D has dramatically helped regulate my immune system. This year, I barely needed other medications. After starting my regimen, my symptoms, which once made spring unbearable, have diminished significantly. It's made a noticeable difference.
Read More
9
Prevents illnesses effectively
2 people found this helpful
During the seasonal viral infections, we consistently take this vitamin. It effectively boosts our immunity, and we have largely forgotten what it feels like to have colds and flu. It's been a reliable component of our health regimen.
Read More
7.5
Essential for family health
2 people found this helpful
My family takes vitamin D daily, recognising its importance for overall health. I've learned that it activates the immune system and combats various health issues. With such high numbers of COVID-19 patients lacking this vitamin, we've made it a part of our daily routine. Each of us has a tailored dosage; I take 5000 units a day.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.2
  • All Researches
9
Vitamin D's role in ear infections
We investigated how vitamin D levels affect the occurrence of ear infections, specifically in children aged 2 to 7. By looking at data from a pediatric clinic in northwest Romania, we enrolled 118 children—87 with recent ear infections and 31 who hadn't experienced any episodes. This allowed us to compare vitamin D levels across different types of ear infections, like Acute Suppurative Otitis Media and Serous Otitis Media.

Our findings revealed that children suffering from these infections had notably lower vitamin D levels compared to the control group. The children with Acute Suppurative Otitis Media showed the most significant deficiencies. We found a clear link: as vitamin D levels decreased, the frequency of ear infections increased. Logistic regression pointed out that vitamin D insufficiency boosted the odds of ear infections significantly, while Poisson regression established a strong correlation between low vitamin D status and the incidence of these infections.

Overall, these results indicate that low serum vitamin D may play a critical role in the risk of developing ear infections in young children. This suggests that screening and potentially supplementing vitamin D could be valuable strategies for reducing the frequency of ear infections and their associated complications. By addressing this modifiable risk factor, we can help improve the health and quality of life for many children.
Read More
9
Vitamin D enhances tympanoplasty outcomes
We explored how vitamin D (VD) levels influence the outcomes for patients undergoing Type 1 tympanoplasty (T1T), which is a common surgery for chronic ear infections. In our study, we divided 101 patients into four groups based on their VD levels, ranging from severe insufficiency to optimal levels.

Over a 12-month follow-up, we observed that patients with optimal VD levels had significantly higher graft success rates and greater improvements in hearing. Additionally, these patients experienced fewer postoperative infections.

Our findings highlight the importance of monitoring vitamin D levels in patients with chronic ear issues. We believe that addressing VD deficiency could enhance the success of tympanoplasty, suggesting that vitamin D replacement therapy might be beneficial for those with low preoperative levels.
Read More
8
Vitamin D levels linked to cholesteatoma
We conducted a study to explore the relationship between vitamin D levels and ear cholesteatoma, a type of middle ear infection. Our research included 62 patients diagnosed with cholesteatoma and compared them with a control group of 62 patients with simple chronic otitis media. Both groups were similar in age and gender, which allowed us to focus solely on the differences in vitamin D levels.

After analyzing the data, we found that vitamin D levels were significantly lower in patients with cholesteatoma compared to those in the control group. This suggests that there might be a connection between low vitamin D levels and the development of cholesteatoma. Furthermore, we noticed that lower vitamin D levels were associated with increased symptoms like hearing loss, tinnitus, and vertigo.

While our findings indicate that vitamin D deficiency could be linked to ear cholesteatoma, we did not evaluate the direct effects of vitamin D treatment on ear infections. Therefore, while vitamin D appears to play a role in this condition, more research is needed to determine whether supplementation might help with symptoms or improve outcomes in patients suffering from cholesteatoma.
Read More
8
Vitamin D may reduce ear infections
We explored the connection between vitamin D levels and chronic otitis media with effusion (COME) in children. In a well-structured case-control study, we analyzed serum 25(OH)D concentrations in 178 children who were referred for tympanostomy tube placement due to COME, compared to 179 healthy children. Our subjects, aged three and four, were recruited from Auckland, New Zealand, and data was collected from May 2011 to November 2013.

Our findings revealed that higher serum 25(OH)D levels were associated with a lower risk of COME. Specifically, with each 10 nmol/L increase in vitamin D levels, the odds of developing COME decreased significantly, even after adjusting for various factors such as age, sex, and breastfeeding duration. This indicates that vitamin D may play a protective role against this type of ear infection.

These results encourage further investigation into whether increasing vitamin D levels—through sun exposure, dietary changes, or supplements—could effectively reduce the risk of ear infections in children. It highlights an area of vitamin D's potential benefits that warrants additional exploration.
Read More
We explored the relationship between vitamin D (VD) supplementation and the risk of ear infections, specifically in children who frequently suffer from acute otitis media (AOM). The study involved 116 children with a history of recurrent ear infections, who were randomly assigned to receive either a daily dose of 1000 IU of vitamin D or a placebo for four months. Their number of AOM episodes was monitored for six months after the treatment period.

Our findings were quite revealing: the children who received vitamin D supplements had a significantly lower incidence of AOM compared to those who were given the placebo. Specifically, only 26 children in the vitamin D group experienced at least one episode of AOM, versus 38 in the placebo group—a notable difference that became even more pronounced when looking specifically at uncomplicated AOM cases.

We concluded that vitamin D deficiency is common among children who frequently experience ear infections. By restoring serum vitamin D levels to above 30 ng/mL through supplementation, we observed a significant reduction in the risk of uncomplicated AOM. This suggests that vitamin D could play a beneficial role in managing ear infections in children prone to these issues.
Read More

User Reviews

USERS' SCORE
Good
Based on 13 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective hay fever treatment
2 people found this helpful
As someone who suffers from hay fever, I found that taking vitamin D has dramatically helped regulate my immune system. This year, I barely needed other medications. After starting my regimen, my symptoms, which once made spring unbearable, have diminished significantly. It's made a noticeable difference.
Read More
9
Prevents illnesses effectively
2 people found this helpful
During the seasonal viral infections, we consistently take this vitamin. It effectively boosts our immunity, and we have largely forgotten what it feels like to have colds and flu. It's been a reliable component of our health regimen.
Read More
7.5
Essential for family health
2 people found this helpful
My family takes vitamin D daily, recognising its importance for overall health. I've learned that it activates the immune system and combats various health issues. With such high numbers of COVID-19 patients lacking this vitamin, we've made it a part of our daily routine. Each of us has a tailored dosage; I take 5000 units a day.
Read More
9
Promotes overall health
1 people found this helpful
Excellent increases vitamin D in the blood. Two months after taking it, I had my vitamin D levels checked and saw excellent promotion in my health. I also noticed a reduction in colds and acute respiratory infections, much to my delight. This is particularly noteworthy during the pandemic. I highly recommend it to everyone.
Read More
9
Reduces infections in children
1 people found this helpful
I give my children this vitamin D dosage all year round. Since starting it, their acute respiratory infections have significantly decreased, allowing them to attend kindergarten without issues. Even when they do catch colds, they recover easily without complications. It's been a great addition to our family’s health routine.
Read More

Frequently Asked Questions

9
Promotes overall health
1 people found this helpful
Excellent increases vitamin D in the blood. Two months after taking it, I had my vitamin D levels checked and saw excellent promotion in my health. I also noticed a reduction in colds and acute respiratory infections, much to my delight. This is particularly noteworthy during the pandemic. I highly recommend it to everyone.
9
Alleviated chronic conditions
1 people found this helpful
After transitioning to a higher dosage of vitamin D, my wife’s long-standing night sweats and depression improved immensely. She’s now full of energy and her general health has drastically changed. Similarly, my own chronic angina has disappeared over the past month, likely due to this new regimen.
7.5
Boosts vitality significantly
1 people found this helpful
I have been taking this vitamin daily for about a year at a dosage of 5000 units. Initially, I experienced terrible deficiency, but my health has dramatically improved. I no longer suffer from dizziness, and I wake up feeling energetic. Previously, I caught colds six to seven times a year, but now I've only had one since early autumn and recovered quickly. This vitamin truly works wonders.
9
Effective hay fever treatment
2 people found this helpful
As someone who suffers from hay fever, I found that taking vitamin D has dramatically helped regulate my immune system. This year, I barely needed other medications. After starting my regimen, my symptoms, which once made spring unbearable, have diminished significantly. It's made a noticeable difference.
9
Prevents illnesses effectively
2 people found this helpful
During the seasonal viral infections, we consistently take this vitamin. It effectively boosts our immunity, and we have largely forgotten what it feels like to have colds and flu. It's been a reliable component of our health regimen.
9
Reduces infections in children
1 people found this helpful
I give my children this vitamin D dosage all year round. Since starting it, their acute respiratory infections have significantly decreased, allowing them to attend kindergarten without issues. Even when they do catch colds, they recover easily without complications. It's been a great addition to our family’s health routine.
We explored the relationship between vitamin D (VD) supplementation and the risk of ear infections, specifically in children who frequently suffer from acute otitis media (AOM). The study involved 116 children with a history of recurrent ear infections, who were randomly assigned to receive either a daily dose of 1000 IU of vitamin D or a placebo for four months. Their number of AOM episodes was monitored for six months after the treatment period.

Our findings were quite revealing: the children who received vitamin D supplements had a significantly lower incidence of AOM compared to those who were given the placebo. Specifically, only 26 children in the vitamin D group experienced at least one episode of AOM, versus 38 in the placebo group—a notable difference that became even more pronounced when looking specifically at uncomplicated AOM cases.

We concluded that vitamin D deficiency is common among children who frequently experience ear infections. By restoring serum vitamin D levels to above 30 ng/mL through supplementation, we observed a significant reduction in the risk of uncomplicated AOM. This suggests that vitamin D could play a beneficial role in managing ear infections in children prone to these issues.
9
Vitamin D's role in ear infections
We investigated how vitamin D levels affect the occurrence of ear infections, specifically in children aged 2 to 7. By looking at data from a pediatric clinic in northwest Romania, we enrolled 118 children—87 with recent ear infections and 31 who hadn't experienced any episodes. This allowed us to compare vitamin D levels across different types of ear infections, like Acute Suppurative Otitis Media and Serous Otitis Media.

Our findings revealed that children suffering from these infections had notably lower vitamin D levels compared to the control group. The children with Acute Suppurative Otitis Media showed the most significant deficiencies. We found a clear link: as vitamin D levels decreased, the frequency of ear infections increased. Logistic regression pointed out that vitamin D insufficiency boosted the odds of ear infections significantly, while Poisson regression established a strong correlation between low vitamin D status and the incidence of these infections.

Overall, these results indicate that low serum vitamin D may play a critical role in the risk of developing ear infections in young children. This suggests that screening and potentially supplementing vitamin D could be valuable strategies for reducing the frequency of ear infections and their associated complications. By addressing this modifiable risk factor, we can help improve the health and quality of life for many children.
8
Vitamin D may reduce ear infections
We explored the connection between vitamin D levels and chronic otitis media with effusion (COME) in children. In a well-structured case-control study, we analyzed serum 25(OH)D concentrations in 178 children who were referred for tympanostomy tube placement due to COME, compared to 179 healthy children. Our subjects, aged three and four, were recruited from Auckland, New Zealand, and data was collected from May 2011 to November 2013.

Our findings revealed that higher serum 25(OH)D levels were associated with a lower risk of COME. Specifically, with each 10 nmol/L increase in vitamin D levels, the odds of developing COME decreased significantly, even after adjusting for various factors such as age, sex, and breastfeeding duration. This indicates that vitamin D may play a protective role against this type of ear infection.

These results encourage further investigation into whether increasing vitamin D levels—through sun exposure, dietary changes, or supplements—could effectively reduce the risk of ear infections in children. It highlights an area of vitamin D's potential benefits that warrants additional exploration.
We aimed to understand how vitamin D levels might influence recurrent ear infections, specifically otitis media, in young children. By comparing the serum vitamin D levels of 84 children suffering from recurrent ear infections to 108 healthy peers, we could explore the potential link between vitamin D deficiency and this common childhood ailment.

Our findings revealed that a significant number of children with recurrent otitis media had low vitamin D levels, with an average serum level of just 11.4 ng/mL. In contrast, the healthy control group had an average level of 29.2 ng/mL. Notably, the majority of children in the study group—about 69%—had vitamin D levels below the 20 ng/mL threshold, which is often considered deficient.

To address this deficiency, children who were found to have low vitamin D levels received vitamin D therapy alongside their standard treatment for the ear infections. Over the course of one-year follow-up, we observed that vitamin D supplementation seemed to contribute positively, as only a handful of infections occurred during that period.

While our study did show a correlation between low vitamin D levels and recurrent ear infections, it’s essential to mention that the vitamin D treatment was given alongside conventional therapies. Thus, we cannot definitively conclude that vitamin D alone was responsible for reducing ear infections. Nevertheless, it suggests that integrating vitamin D supplementation could be a beneficial approach in managing recurrent otitis media in children.

References

  1. Manole A, Mărcuț LF, Cârciumaru R, Manole F. Preventing Recurrent Otitis Media in Children Aged 2-7 Years: A Cross-Sectional Evaluation of Serum Vitamin D as a Modifiable Factor. Diagnostics (Basel). 2025;15. doi:10.3390/diagnostics15050519
  2. Kelleş M, Guler Y, Guler R. Vitamin D: A Factor affecting the Success of Type 1 Tympanoplasty. Ear Nose Throat J. 2022. doi:10.1177/01455613221137224
  3. Fanimolky F, Amizadeh M. Investigation of the Serum Level of Vitamin D in Patients with Ear Cholesteatoma. Iran J Otorhinolaryngol. 2022;34:89. doi:10.22038/IJORL.2021.52513.2793
  4. Kim HB, Lim SH, Cho CG, Choi HS. Influence of Vitamin D Deficiency on Progression of Experimental Otitis Media in Rats. Endocrinol Metab (Seoul). 2018;33:296. doi:10.3803/EnM.2018.33.2.296
  5. Akcan FA, Dündar Y, Akcan HB, Uluat A, Cebeci D, et al. Clinical role of vitamin D in prognosis of otitis media with effusion. Int J Pediatr Otorhinolaryngol. 2018;105:1. doi:10.1016/j.ijporl.2017.11.030
  6. Walker RE, Bartley J, Camargo CA, Flint D, Thompson JMD, et al. Higher serum 25(OH)D concentration is associated with lower risk of chronic otitis media with effusion: a case-control study. Acta Paediatr. 2017;106:1487. doi:10.1111/apa.13908
  7. Li HB, Tai XH, Sang YH, Jia JP, Xu ZM, et al. Association between vitamin D and development of otitis media: A PRISMA-compliant meta-analysis and systematic review. Medicine (Baltimore). 2016;95:e4739. doi:10.1097/MD.0000000000004739
  8. Cayir A, Turan MI, Ozkan O, Cayir Y. Vitamin D levels in children diagnosed with acute otitis media. J Pak Med Assoc. 2014;64:1274.
  9. Marchisio P, Consonni D, Baggi E, Zampiero A, Bianchini S, et al. Vitamin D supplementation reduces the risk of acute otitis media in otitis-prone children. Pediatr Infect Dis J. 2013;32:1055. doi:10.1097/INF.0b013e31829be0b0
  10. Cayir A, Turan MI, Ozkan O, Cayir Y, Kaya A, et al. Serum vitamin D levels in children with recurrent otitis media. Eur Arch Otorhinolaryngol. 2014;271:689. doi:10.1007/s00405-013-2455-7
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