We explored the relationship between vitamin D (VD) supplementation and the risk of ear infections, specifically in children who frequently suffer from acute otitis media (AOM). The study involved 116 children with a history of recurrent ear infections, who were randomly assigned to receive either a daily dose of 1000 IU of vitamin D or a placebo for four months. Their number of AOM episodes was monitored for six months after the treatment period.
Our findings were quite revealing: the children who received vitamin D supplements had a significantly lower incidence of AOM compared to those who were given the placebo. Specifically, only 26 children in the vitamin D group experienced at least one episode of AOM, versus 38 in the placebo group—a notable difference that became even more pronounced when looking specifically at uncomplicated AOM cases.
We concluded that vitamin D deficiency is common among children who frequently experience ear infections. By restoring serum vitamin D levels to above 30 ng/mL through supplementation, we observed a significant reduction in the risk of uncomplicated AOM. This suggests that vitamin D could play a beneficial role in managing ear infections in children prone to these issues.
Read More
9
Vitamin D's role in ear infections
Preventing Recurrent Otitis Media in Children Aged 2-7 Years: A Cross-Sectional Evaluation of Serum Vitamin D as a Modifiable Factor.
We investigated how vitamin D levels affect the occurrence of ear infections, specifically in children aged 2 to 7. By looking at data from a pediatric clinic in northwest Romania, we enrolled 118 children—87 with recent ear infections and 31 who hadn't experienced any episodes. This allowed us to compare vitamin D levels across different types of ear infections, like Acute Suppurative Otitis Media and Serous Otitis Media.
Our findings revealed that children suffering from these infections had notably lower vitamin D levels compared to the control group. The children with Acute Suppurative Otitis Media showed the most significant deficiencies. We found a clear link: as vitamin D levels decreased, the frequency of ear infections increased. Logistic regression pointed out that vitamin D insufficiency boosted the odds of ear infections significantly, while Poisson regression established a strong correlation between low vitamin D status and the incidence of these infections.
Overall, these results indicate that low serum vitamin D may play a critical role in the risk of developing ear infections in young children. This suggests that screening and potentially supplementing vitamin D could be valuable strategies for reducing the frequency of ear infections and their associated complications. By addressing this modifiable risk factor, we can help improve the health and quality of life for many children.
Read More
9
Vitamin D enhances tympanoplasty outcomes
Vitamin D: A Factor affecting the Success of Type 1 Tympanoplasty.
We explored how vitamin D (VD) levels influence the outcomes for patients undergoing Type 1 tympanoplasty (T1T), which is a common surgery for chronic ear infections. In our study, we divided 101 patients into four groups based on their VD levels, ranging from severe insufficiency to optimal levels.
Over a 12-month follow-up, we observed that patients with optimal VD levels had significantly higher graft success rates and greater improvements in hearing. Additionally, these patients experienced fewer postoperative infections.
Our findings highlight the importance of monitoring vitamin D levels in patients with chronic ear issues. We believe that addressing VD deficiency could enhance the success of tympanoplasty, suggesting that vitamin D replacement therapy might be beneficial for those with low preoperative levels.
Read More
Most Useful Reviews
9
Effective hay fever treatment
2 people found this helpful
As someone who suffers from hay fever, I found that taking vitamin D has dramatically helped regulate my immune system. This year, I barely needed other medications. After starting my regimen, my symptoms, which once made spring unbearable, have diminished significantly. It's made a noticeable difference.
Read More
9
Prevents illnesses effectively
2 people found this helpful
During the seasonal viral infections, we consistently take this vitamin. It effectively boosts our immunity, and we have largely forgotten what it feels like to have colds and flu. It's been a reliable component of our health regimen.
Read More
7.5
Essential for family health
2 people found this helpful
My family takes vitamin D daily, recognising its importance for overall health. I've learned that it activates the immune system and combats various health issues. With such high numbers of COVID-19 patients lacking this vitamin, we've made it a part of our daily routine. Each of us has a tailored dosage; I take 5000 units a day.
We investigated how vitamin D levels affect the occurrence of ear infections, specifically in children aged 2 to 7. By looking at data from a pediatric clinic in northwest Romania, we enrolled 118 children—87 with recent ear infections and 31 who hadn't experienced any episodes. This allowed us to compare vitamin D levels across different types of ear infections, like Acute Suppurative Otitis Media and Serous Otitis Media.
Our findings revealed that children suffering from these infections had notably lower vitamin D levels compared to the control group. The children with Acute Suppurative Otitis Media showed the most significant deficiencies. We found a clear link: as vitamin D levels decreased, the frequency of ear infections increased. Logistic regression pointed out that vitamin D insufficiency boosted the odds of ear infections significantly, while Poisson regression established a strong correlation between low vitamin D status and the incidence of these infections.
Overall, these results indicate that low serum vitamin D may play a critical role in the risk of developing ear infections in young children. This suggests that screening and potentially supplementing vitamin D could be valuable strategies for reducing the frequency of ear infections and their associated complications. By addressing this modifiable risk factor, we can help improve the health and quality of life for many children.
Read More
9
Vitamin D enhances tympanoplasty outcomes
Vitamin D: A Factor affecting the Success of Type 1 Tympanoplasty.
We explored how vitamin D (VD) levels influence the outcomes for patients undergoing Type 1 tympanoplasty (T1T), which is a common surgery for chronic ear infections. In our study, we divided 101 patients into four groups based on their VD levels, ranging from severe insufficiency to optimal levels.
Over a 12-month follow-up, we observed that patients with optimal VD levels had significantly higher graft success rates and greater improvements in hearing. Additionally, these patients experienced fewer postoperative infections.
Our findings highlight the importance of monitoring vitamin D levels in patients with chronic ear issues. We believe that addressing VD deficiency could enhance the success of tympanoplasty, suggesting that vitamin D replacement therapy might be beneficial for those with low preoperative levels.
Read More
8
Vitamin D levels linked to cholesteatoma
Investigation of the Serum Level of Vitamin D in Patients with Ear Cholesteatoma.
We conducted a study to explore the relationship between vitamin D levels and ear cholesteatoma, a type of middle ear infection. Our research included 62 patients diagnosed with cholesteatoma and compared them with a control group of 62 patients with simple chronic otitis media. Both groups were similar in age and gender, which allowed us to focus solely on the differences in vitamin D levels.
After analyzing the data, we found that vitamin D levels were significantly lower in patients with cholesteatoma compared to those in the control group. This suggests that there might be a connection between low vitamin D levels and the development of cholesteatoma. Furthermore, we noticed that lower vitamin D levels were associated with increased symptoms like hearing loss, tinnitus, and vertigo.
While our findings indicate that vitamin D deficiency could be linked to ear cholesteatoma, we did not evaluate the direct effects of vitamin D treatment on ear infections. Therefore, while vitamin D appears to play a role in this condition, more research is needed to determine whether supplementation might help with symptoms or improve outcomes in patients suffering from cholesteatoma.
Read More
8
Vitamin D may reduce ear infections
Higher serum 25(OH)D concentration is associated with lower risk of chronic otitis media with effusion: a case-control study.
We explored the connection between vitamin D levels and chronic otitis media with effusion (COME) in children. In a well-structured case-control study, we analyzed serum 25(OH)D concentrations in 178 children who were referred for tympanostomy tube placement due to COME, compared to 179 healthy children. Our subjects, aged three and four, were recruited from Auckland, New Zealand, and data was collected from May 2011 to November 2013.
Our findings revealed that higher serum 25(OH)D levels were associated with a lower risk of COME. Specifically, with each 10 nmol/L increase in vitamin D levels, the odds of developing COME decreased significantly, even after adjusting for various factors such as age, sex, and breastfeeding duration. This indicates that vitamin D may play a protective role against this type of ear infection.
These results encourage further investigation into whether increasing vitamin D levels—through sun exposure, dietary changes, or supplements—could effectively reduce the risk of ear infections in children. It highlights an area of vitamin D's potential benefits that warrants additional exploration.
Read More
8
Vitamin D reduces ear infection risk
Vitamin D supplementation reduces the risk of acute otitis media in otitis-prone children.
We explored the relationship between vitamin D (VD) supplementation and the risk of ear infections, specifically in children who frequently suffer from acute otitis media (AOM). The study involved 116 children with a history of recurrent ear infections, who were randomly assigned to receive either a daily dose of 1000 IU of vitamin D or a placebo for four months. Their number of AOM episodes was monitored for six months after the treatment period.
Our findings were quite revealing: the children who received vitamin D supplements had a significantly lower incidence of AOM compared to those who were given the placebo. Specifically, only 26 children in the vitamin D group experienced at least one episode of AOM, versus 38 in the placebo group—a notable difference that became even more pronounced when looking specifically at uncomplicated AOM cases.
We concluded that vitamin D deficiency is common among children who frequently experience ear infections. By restoring serum vitamin D levels to above 30 ng/mL through supplementation, we observed a significant reduction in the risk of uncomplicated AOM. This suggests that vitamin D could play a beneficial role in managing ear infections in children prone to these issues.
As someone who suffers from hay fever, I found that taking vitamin D has dramatically helped regulate my immune system. This year, I barely needed other medications. After starting my regimen, my symptoms, which once made spring unbearable, have diminished significantly. It's made a noticeable difference.
Read More
9
Prevents illnesses effectively
2 people found this helpful
During the seasonal viral infections, we consistently take this vitamin. It effectively boosts our immunity, and we have largely forgotten what it feels like to have colds and flu. It's been a reliable component of our health regimen.
Read More
7.5
Essential for family health
2 people found this helpful
My family takes vitamin D daily, recognising its importance for overall health. I've learned that it activates the immune system and combats various health issues. With such high numbers of COVID-19 patients lacking this vitamin, we've made it a part of our daily routine. Each of us has a tailored dosage; I take 5000 units a day.
Read More
9
Promotes overall health
1 people found this helpful
Excellent increases vitamin D in the blood. Two months after taking it, I had my vitamin D levels checked and saw excellent promotion in my health. I also noticed a reduction in colds and acute respiratory infections, much to my delight. This is particularly noteworthy during the pandemic. I highly recommend it to everyone.
Read More
9
Reduces infections in children
1 people found this helpful
I give my children this vitamin D dosage all year round. Since starting it, their acute respiratory infections have significantly decreased, allowing them to attend kindergarten without issues. Even when they do catch colds, they recover easily without complications. It's been a great addition to our family’s health routine.
An ear infection, also known as otitis media, occurs when germs—such as bacteria or viruses—infect the middle ear, which is the space behind the eardrum. This condition can cause a variety of symptoms, including ear pain, difficulty hearing, fluid drainage from the ear, fever, and irritability in children. Ear infections are particularly common in children due to their shorter and more horizontal Eustachian tubes, which make it easier for pathogens to reach the middle ear. When the Eustachian tubes become swollen or blocked due to upper respiratory infections, allergies, or sinus infections, fluid can accumulate and lead to an infection.
Treatment typically depends on the severity and frequency of the infections. For mild cases, doctors may recommend observation, as many ear infections resolve on their own. In more severe cases, particularly when symptoms last longer than 48 hours, antibiotics may be prescribed. Pain relievers can also help manage discomfort. In cases of recurrent infections, additional interventions, such as the placement of ear tubes, might be considered. Proper hygiene and avoiding exposure to smoke can also reduce the risk of developing ear infections.
Vitamin D is a fat-soluble vitamin that's essential for maintaining healthy bones and teeth, supporting immune system function, and facilitating normal cell growth and development. It plays a crucial role in calcium absorption in the gut, which is vital for bone health. Unlike most vitamins, our bodies can produce Vitamin D when exposed to sunlight, specifically UVB rays, which is why it’s often referred to as the "sunshine vitamin." However, depending on your geographical location, lifestyle, and skin type, getting sufficient Vitamin D from the sun alone can be challenging, particularly during the winter months.
In addition to sunlight, Vitamin D can be obtained from certain foods such as fatty fish (like salmon and mackerel), fish liver oils, and fortified foods like milk and cereals. Some individuals may also consider supplements, especially if they're at risk for deficiency. Insufficient vitamin D levels are linked to various health issues, including rickets in children, osteomalacia in adults, and even an increased risk of chronic diseases. Regularly checking your vitamin D levels and consulting with a healthcare professional can help ensure you're meeting your needs for optimal health.
Vitamin D plays a vital role in immune function, which can theoretically impact the body's ability to fend off infections, including ear infections. Some studies suggest that adequate levels of vitamin D may help reduce the risk of respiratory infections, and by extension, they could potentially influence the incidence of ear infections, especially in children. It's important to note, however, that vitamin D should not be viewed as a standalone treatment for ear infections.
If you or your child is experiencing symptoms of an ear infection, such as pain, fluid drainage, or fever, it’s crucial to consult a healthcare professional for proper diagnosis and treatment. They may recommend antibiotics or other therapies, depending on the severity and nature of the infection. While maintaining sufficient vitamin D levels can support overall health, it's not a guaranteed preventative measure against ear infections, and a multidimensional approach—including medical treatment—is usually necessary for effective management.
Based on user reviews, the time frame to see results from taking vitamin D varies among individuals, but many report noticing positive changes within a few weeks to a couple of months. For example, one user mentioned that after two months of supplementation, they experienced an increase in vitamin D levels and a reduction in respiratory infections Read Review. Another user observed significant improvements in their overall health after transitioning to a higher dosage, which included a positive shift within just a month Read Review.
Additionally, there are users who reported long-term benefits from consistent vitamin D intake, reinforcing its role in maintaining a robust immune system. One individual shared that since beginning a daily regimen about a year ago, they have experienced a notable drop in the frequency of colds, suggesting that cumulative benefits may become pronounced with ongoing use Read Review. Overall, while initial improvements can be quick, sustained benefits appear to manifest over a longer period, depending on individual health conditions and dosage.
Vitamin D supplementation may have potential benefits for managing ear infections, particularly in children. A study showed that children with recurrent acute otitis media had significantly lower vitamin D levels compared to healthy controls, suggesting a possible link between vitamin D deficiency and ear infections [9]. Specifically, children receiving vitamin D supplements exhibited a notable reduction in the incidence of these infections when compared to those given a placebo, providing evidence that maintaining adequate vitamin D levels might help prevent acute ear infections [9].
Further research supports the idea that low vitamin D levels are associated with various types of ear infections. For instance, a study found that children suffering from acute suppurative otitis media had markedly lower vitamin D levels than a control group, indicating that sufficient vitamin D may play an important role in reducing the risk of ear infections [1]. While these findings are promising, it's crucial to understand that more extensive research is needed to establish definitive correlations and treatment guidelines. Therefore, while the current evidence suggests a supportive role for vitamin D in ear health, it should be viewed as part of a broader approach to managing ear infections in children.
Users have reported a variety of improvements in their symptoms after starting vitamin D supplementation, with many experiences highlighting significant boosts to immune function. For instance, one individual suffering from hay fever noted that their symptoms had dramatically improved, allowing them to reduce reliance on other medications during allergy season Read Review. Another reviewer stated that consistent vitamin D intake has led to a noticeable decrease in the frequency of colds and flu, emphasizing its effectiveness during seasonal viral infections Read Review.
Moreover, several users mentioned overall health improvements. One person reported alleviation of long-standing night sweats and depression after increasing their dosage, while another noted a marked decline in dizziness and fatigue after addressing their vitamin D deficiency Read ReviewRead Review. Families taking vitamin D indicated fewer occurrences of acute respiratory infections in children, facilitating better attendance at school without complications Read Review. While these anecdotal experiences underscore the vitamin's potential benefits, it's essential to note that individual results may vary based on factors such as dosage, health status, and lifestyle.
Users have shared various insights regarding the combination of vitamin D with other supplements or treatments for managing ear infections. While many do not provide a direct correlation to ear infections specifically, the overarching theme suggests that vitamin D enhances immune function, which may indirectly help combat infections. One user reported that since incorporating vitamin D into their regimen, they have experienced reduced respiratory infections, allowing their children to recover easily from colds Read Review. This implies a potential benefit for preventing infections that may lead to complications such as ear infections.
Moreover, some users noted that vitamin D supplementation significantly improved their overall health and reduced the frequency of illnesses, which could be advantageous for those prone to ear infections Read Review. Similarly, families reported fewer incidents of acute respiratory infections, suggesting a potential protective effect that may also extend to ear health Read Review. While firm evidence regarding its use specifically for ear infections remains elusive, the general consensus leans towards vitamin D's vital role in bolstering immune defenses and promoting recovery.
Recent research indicates that vitamin D may play a significant role in managing ear infections, particularly in children. A notable study involving 116 children with a history of recurrent ear infections demonstrated that a daily dose of 1000 IU of vitamin D significantly reduced the incidence of acute otitis media (AOM) compared to a placebo group, with many participants seeing serum vitamin D levels restored above 30 ng/mL after supplementation [9]. Another investigation revealed that children with higher serum vitamin D levels had a lower risk of developing chronic otitis media with effusion, suggesting potential protective effects against such infections [6].
Moreover, overall findings suggest that maintaining sufficient vitamin D levels—around 20 ng/mL or higher—could play a crucial role in reducing the risk of ear infections [10]. While more comprehensive studies are needed to establish clear treatment protocols, current evidence supports the idea that vitamin D supplementation, especially at around 1000 IU daily, may be beneficial in decreasing ear infection frequency and improving overall ear health in prone populations.
9
Promotes overall health
1 people found this helpful
Excellent increases vitamin D in the blood. Two months after taking it, I had my vitamin D levels checked and saw excellent promotion in my health. I also noticed a reduction in colds and acute respiratory infections, much to my delight. This is particularly noteworthy during the pandemic. I highly recommend it to everyone.
9
Alleviated chronic conditions
1 people found this helpful
After transitioning to a higher dosage of vitamin D, my wife’s long-standing night sweats and depression improved immensely. She’s now full of energy and her general health has drastically changed. Similarly, my own chronic angina has disappeared over the past month, likely due to this new regimen.
7.5
Boosts vitality significantly
1 people found this helpful
I have been taking this vitamin daily for about a year at a dosage of 5000 units. Initially, I experienced terrible deficiency, but my health has dramatically improved. I no longer suffer from dizziness, and I wake up feeling energetic. Previously, I caught colds six to seven times a year, but now I've only had one since early autumn and recovered quickly. This vitamin truly works wonders.
9
Effective hay fever treatment
2 people found this helpful
As someone who suffers from hay fever, I found that taking vitamin D has dramatically helped regulate my immune system. This year, I barely needed other medications. After starting my regimen, my symptoms, which once made spring unbearable, have diminished significantly. It's made a noticeable difference.
9
Prevents illnesses effectively
2 people found this helpful
During the seasonal viral infections, we consistently take this vitamin. It effectively boosts our immunity, and we have largely forgotten what it feels like to have colds and flu. It's been a reliable component of our health regimen.
9
Reduces infections in children
1 people found this helpful
I give my children this vitamin D dosage all year round. Since starting it, their acute respiratory infections have significantly decreased, allowing them to attend kindergarten without issues. Even when they do catch colds, they recover easily without complications. It's been a great addition to our family’s health routine.
8
Vitamin D reduces ear infection risk
Vitamin D supplementation reduces the risk of acute otitis media in otitis-prone children.
We explored the relationship between vitamin D (VD) supplementation and the risk of ear infections, specifically in children who frequently suffer from acute otitis media (AOM). The study involved 116 children with a history of recurrent ear infections, who were randomly assigned to receive either a daily dose of 1000 IU of vitamin D or a placebo for four months. Their number of AOM episodes was monitored for six months after the treatment period.
Our findings were quite revealing: the children who received vitamin D supplements had a significantly lower incidence of AOM compared to those who were given the placebo. Specifically, only 26 children in the vitamin D group experienced at least one episode of AOM, versus 38 in the placebo group—a notable difference that became even more pronounced when looking specifically at uncomplicated AOM cases.
We concluded that vitamin D deficiency is common among children who frequently experience ear infections. By restoring serum vitamin D levels to above 30 ng/mL through supplementation, we observed a significant reduction in the risk of uncomplicated AOM. This suggests that vitamin D could play a beneficial role in managing ear infections in children prone to these issues.
9
Vitamin D's role in ear infections
Preventing Recurrent Otitis Media in Children Aged 2-7 Years: A Cross-Sectional Evaluation of Serum Vitamin D as a Modifiable Factor.
We investigated how vitamin D levels affect the occurrence of ear infections, specifically in children aged 2 to 7. By looking at data from a pediatric clinic in northwest Romania, we enrolled 118 children—87 with recent ear infections and 31 who hadn't experienced any episodes. This allowed us to compare vitamin D levels across different types of ear infections, like Acute Suppurative Otitis Media and Serous Otitis Media.
Our findings revealed that children suffering from these infections had notably lower vitamin D levels compared to the control group. The children with Acute Suppurative Otitis Media showed the most significant deficiencies. We found a clear link: as vitamin D levels decreased, the frequency of ear infections increased. Logistic regression pointed out that vitamin D insufficiency boosted the odds of ear infections significantly, while Poisson regression established a strong correlation between low vitamin D status and the incidence of these infections.
Overall, these results indicate that low serum vitamin D may play a critical role in the risk of developing ear infections in young children. This suggests that screening and potentially supplementing vitamin D could be valuable strategies for reducing the frequency of ear infections and their associated complications. By addressing this modifiable risk factor, we can help improve the health and quality of life for many children.
8
Vitamin D may reduce ear infections
Higher serum 25(OH)D concentration is associated with lower risk of chronic otitis media with effusion: a case-control study.
We explored the connection between vitamin D levels and chronic otitis media with effusion (COME) in children. In a well-structured case-control study, we analyzed serum 25(OH)D concentrations in 178 children who were referred for tympanostomy tube placement due to COME, compared to 179 healthy children. Our subjects, aged three and four, were recruited from Auckland, New Zealand, and data was collected from May 2011 to November 2013.
Our findings revealed that higher serum 25(OH)D levels were associated with a lower risk of COME. Specifically, with each 10 nmol/L increase in vitamin D levels, the odds of developing COME decreased significantly, even after adjusting for various factors such as age, sex, and breastfeeding duration. This indicates that vitamin D may play a protective role against this type of ear infection.
These results encourage further investigation into whether increasing vitamin D levels—through sun exposure, dietary changes, or supplements—could effectively reduce the risk of ear infections in children. It highlights an area of vitamin D's potential benefits that warrants additional exploration.
8
Vitamin D's role in ear infections
Serum vitamin D levels in children with recurrent otitis media.
We aimed to understand how vitamin D levels might influence recurrent ear infections, specifically otitis media, in young children. By comparing the serum vitamin D levels of 84 children suffering from recurrent ear infections to 108 healthy peers, we could explore the potential link between vitamin D deficiency and this common childhood ailment.
Our findings revealed that a significant number of children with recurrent otitis media had low vitamin D levels, with an average serum level of just 11.4 ng/mL. In contrast, the healthy control group had an average level of 29.2 ng/mL. Notably, the majority of children in the study group—about 69%—had vitamin D levels below the 20 ng/mL threshold, which is often considered deficient.
To address this deficiency, children who were found to have low vitamin D levels received vitamin D therapy alongside their standard treatment for the ear infections. Over the course of one-year follow-up, we observed that vitamin D supplementation seemed to contribute positively, as only a handful of infections occurred during that period.
While our study did show a correlation between low vitamin D levels and recurrent ear infections, it’s essential to mention that the vitamin D treatment was given alongside conventional therapies. Thus, we cannot definitively conclude that vitamin D alone was responsible for reducing ear infections. Nevertheless, it suggests that integrating vitamin D supplementation could be a beneficial approach in managing recurrent otitis media in children.
References
Manole A, Mărcuț LF, Cârciumaru R, Manole F. Preventing Recurrent Otitis Media in Children Aged 2-7 Years: A Cross-Sectional Evaluation of Serum Vitamin D as a Modifiable Factor. Diagnostics (Basel). 2025;15. doi:10.3390/diagnostics15050519
Kelleş M, Guler Y, Guler R. Vitamin D: A Factor affecting the Success of Type 1 Tympanoplasty. Ear Nose Throat J. 2022. doi:10.1177/01455613221137224
Fanimolky F, Amizadeh M. Investigation of the Serum Level of Vitamin D in Patients with Ear Cholesteatoma. Iran J Otorhinolaryngol. 2022;34:89. doi:10.22038/IJORL.2021.52513.2793
Kim HB, Lim SH, Cho CG, Choi HS. Influence of Vitamin D Deficiency on Progression of Experimental Otitis Media in Rats. Endocrinol Metab (Seoul). 2018;33:296. doi:10.3803/EnM.2018.33.2.296
Akcan FA, Dündar Y, Akcan HB, Uluat A, Cebeci D, et al. Clinical role of vitamin D in prognosis of otitis media with effusion. Int J Pediatr Otorhinolaryngol. 2018;105:1. doi:10.1016/j.ijporl.2017.11.030
Walker RE, Bartley J, Camargo CA, Flint D, Thompson JMD, et al. Higher serum 25(OH)D concentration is associated with lower risk of chronic otitis media with effusion: a case-control study. Acta Paediatr. 2017;106:1487. doi:10.1111/apa.13908
Li HB, Tai XH, Sang YH, Jia JP, Xu ZM, et al. Association between vitamin D and development of otitis media: A PRISMA-compliant meta-analysis and systematic review. Medicine (Baltimore). 2016;95:e4739. doi:10.1097/MD.0000000000004739
Cayir A, Turan MI, Ozkan O, Cayir Y. Vitamin D levels in children diagnosed with acute otitis media. J Pak Med Assoc. 2014;64:1274.
Marchisio P, Consonni D, Baggi E, Zampiero A, Bianchini S, et al. Vitamin D supplementation reduces the risk of acute otitis media in otitis-prone children. Pediatr Infect Dis J. 2013;32:1055. doi:10.1097/INF.0b013e31829be0b0
Cayir A, Turan MI, Ozkan O, Cayir Y, Kaya A, et al. Serum vitamin D levels in children with recurrent otitis media. Eur Arch Otorhinolaryngol. 2014;271:689. doi:10.1007/s00405-013-2455-7